尽管降胆固醇药物具有减慢动脉粥样硬化进程和减少心脏病患者发作的能力,但这些药物在大量的病人中却未发现有明确的疗效。在对无应答遗传因子的研究中,研究者寻找编码胆固醇酯转移蛋白(CETP)基因的多态性,CETP是一种酶,可增加低密度脂蛋白胆固醇的含量并促使动脉粥样硬化。在近期出版的《新英格兰 Although cholesterol-lowering drugs have the potential to slow the progression of atherosclerosis and reduce the incidence of heart attacks, these drugs have not been shown to have a definite therapeutic effect in a large number of patients. In a study of non-response genetic factors, researchers looked for polymorphisms that encode cholesterol ester transfer protein (CETP), an enzyme that increases LDL cholesterol and promotes atherosclerosis. Recently published "New England