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目的分析研究序贯与标准三联疗法针对治疗消化性溃疡的临床效果,指导在临床中的使用。方法选取我院自2009年10月到2011年5月的消化性溃疡患者资料90例,随机分为观察组和对照组,观察组患者使用序贯三联疗法治疗,对照组患者使用标准三联疗法治疗,分析比较两组患者的治疗有效率。结果观察组患者通过治疗的总有效率为91.1%,对照组患者为57.8%,两组进行比较存在明显差异(P<0.05),具有统计学意义;通过检验,观察组患者的Hp根除率为85.0%,对照组患者的Hp根除率为62.5%,观察组和对照组患者的Hp根除率比较存在明显差异(P<0.05),具有统计学意义。结论与标准三联疗法相比较,序贯三联疗法在针对治疗消化性溃疡疾病中可以增强患者的临床治疗效果和Hp根除率,值得在临床中广泛推广使用。
Objective To study the clinical effect of sequential and standard triple therapy in the treatment of peptic ulcer and to guide the use in clinical practice. Methods 90 patients with peptic ulcer in our hospital from October 2009 to May 2011 were randomly divided into observation group and control group. Patients in observation group were treated with sequential triple therapy, and patients in control group were treated with standard triple therapy , Analysis and comparison of two groups of patients treatment efficiency. Results The total effective rate of treatment in observation group was 91.1% and that in control group was 57.8%. There was significant difference between the two groups (P <0.05), which was statistically significant. The Hp eradication rate in observation group was Hp eradication rate was 62.5% in the control group and 85.0% in the control group. There was a significant difference (P <0.05) in the Hp eradication rate between the observation group and the control group, which was statistically significant. Conclusion Compared with the standard triple therapy, sequential triple therapy can improve the clinical efficacy and Hp eradication rate in the treatment of peptic ulcer disease, and should be widely used in clinical practice.