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目的探讨WHO甲状腺容积标准对我国儿童高碘甲状腺肿大的适用性。方法在河北省衡水市随机选取3个水碘中位数在150-300μg/L的高碘乡和1个水碘中位数为105.4μg/L的对照乡,采用单纯随机抽样方法,分别在3个高碘乡和对照乡选取452名和120名8~10岁儿童,用B超测量其甲状腺容积,用WHO和我国甲状腺容积标准判定其甲状腺肿大情况。结果 WHO和我国甲状腺容积标准判定的3个高碘乡儿童甲状腺肿大率为24.6%(111/452)和8.2%(37/452),有显著统计学差异(χ2=44.19,P=0)。两个标准判定的8、9、10岁年龄组肿大率分别为33.7%(31/92)、23.3%(45/193)、21.0%(35/167)和14.1%(13/92)、6.2%(12/193)、7.2%(12/167);男孩和女孩的肿大率分别为27.1%(66/244)、21.6%(45/208)和7.4%(18/244)、9.1%(19/208);均有显著统计学差异。对照乡儿童甲状腺肿大率分别为14.0%(17/120)和4.2%(5/120),有显著差异(χ2=7.18,P=0.007)。结论判定高碘甲状腺肿大时,WHO甲状腺容积标准对我国儿童偏低。
Objective To investigate the applicability of WHO thyroid volumetric standards to high iodine thyroid enlargement in children in China. Methods In Hengshui City of Hebei Province, three high iodine townships with a median of 150-300 μg / L of iodine and one control village with a median iodine of 105.4 μg / L were randomly selected and randomly divided into three groups Three high iodine township and control township selected 452 and 120 children aged 8 to 10, with thyroid volume measured by B ultrasound, with the WHO and thyroid volume standards to determine the situation of goiter. Results The goiter rates of children with high iodine level in WHO and the thyroid volumetric criteria of China were 24.6% (111/452) and 8.2% (37/452) respectively, with significant difference (χ2 = 44.19, P = 0) . The rates of edema in the 8, 9, and 10-year-old age groups were 33.7% (31/92), 23.3% (45/193), 21.0% (35/167) and 14.1% (13/92) 6.2% (12/193) and 7.2% (12/167) respectively. The rates of swelling in boys and girls were 27.1% (66/244), 21.6% (45/208) and 7.4% (18/244), respectively % (19/208); There were significant statistical differences. The goiter rates of children in control township were 14.0% (17/120) and 4.2% (5/120) respectively, with significant differences (χ2 = 7.18, P = 0.007). Conclusions When judging high iodine goiter, WHO thyroid volume standard is low to our country children.