论文部分内容阅读
全反式维甲酸(ATRA),持续每日口服60～80mg,治疗23例急性早幼粒细胞性白血病,10～30天,达完全缓解(CR)17例,占73.9％,达部分缓解(PR)5例,占21.7％,无效未缓解(NR)1例,占4.3％,加用DA或HA化疗方案治疗后,没有发生早期死亡,没有发生弥漫性血管内凝血(DIC),除2例合并感染持续高热不退,病情恶化外,余21例均完全缓解出院,占91.3％。口服ATRA后,15例出现头痛,头晕,12例有口干,1例发生维甲酸综合征。
All-trans retinoic acid (ATRA), continuous oral 60 ~ 80mg, treatment of 23 cases of acute promyelocytic leukemia, 10 to 30 days, complete remission (CR) in 17 cases, accounting for 73.9%, partial remission ( PR (5), accounting for 21.7%, NR (1), accounting for 4.3%. There was no early death and no diffuse intravascular coagulation (DIC) after treatment with DA or HA chemotherapy. Cases of concomitant infections continued to heat up, the condition deteriorated, the remaining 21 cases were completely relieved of discharge, accounting for 91.3%. After oral administration of ATRA, 15 patients developed headache and dizziness, 12 patients had dry mouth, and 1 patient developed retinoid syndrome.