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目的 :探讨长沙地区病毒性脑炎与疱疹病毒感染的关系。方法 :应用间接免疫荧光技术 (IFA)检测病毒性脑炎患者脑脊液或血清中疱疹病毒特异性IgG ,IgM。结果 :92 1例病毒性脑炎患者中有 1 33例 (1 4 4% )诊断为单纯疱疹病毒性脑炎 ,1 0岁以下年龄为发病高峰 ,9例 (0 98% )诊断为巨细胞病毒性脑炎 ,1 2例 (1 3 % )为水痘 带状疱疹病毒性脑炎。结论 :长沙地区疱疹病毒性脑炎病原以单纯疱疹病毒最常见 ;IFA法对疱疹病毒性脑炎具有诊断价值
Objective: To investigate the relationship between viral encephalitis and herpes simplex virus infection in Changsha area. Methods: Herpes simplex IgG and IgM in CSF or serum of patients with viral encephalitis were detected by indirect immunofluorescence assay (IFA). Results: One hundred and thirty-three cases (94.4%) of 92 patients with viral encephalitis were diagnosed as herpes simplex encephalitis, the age of onset was below 10 years old, and 9 cases (0 98%) were diagnosed as giant cells Viral encephalitis, 12 cases (13%) of varicella-zoster virus encephalitis. Conclusion: The herpes simplex virus (HSV) is the most common pathogen of herpes simplex virus in Changsha. IFA has diagnostic value for herpes simplex virus encephalitis