特发性高钙尿症发生在约40％的肾结石病人中,系指每日钙的排泄量在300毫克以上(男)、250毫克以上(女)或 4毫克/公斤体重以上,而血钙正常,没有高钙尿症的特殊原因,如肾小管性酸中毒、结节病、关节僵硬、维生素D过量、甲亢、任何原因引起的糖皮质激素过量、累及骨骼的恶性肿瘤、Pagets病,快速进展的骨质疏松和其它罕见的情况。特发性高钙尿症的原因尚未确定,有许多文献提示存在高钙尿症的遗传方式,但很少有人研究过他们的发生和二者的关系,如草酸钙结石患者的高钙尿症和受累家庭中连 Idiopathic hypercalciuria, occurring in about 40% of patients with kidney stones, means daily calcium excretion is above 300 mg (male), 250 mg (female) or 4 mg / kg body weight, and blood Calcium is normal, there are no specific causes of hypercalciuria such as renal tubular acidosis, sarcoidosis, joint stiffness, excessive vitamin D, hyperthyroidism, glucocorticoid excess due to any cause, malignancy involving bone, Pagets disease, Rapid progression of osteoporosis and other rare conditions. The causes of idiopathic hypercalciuria have not been established yet. Many literatures suggest that there is a genetic mode of hypercalciuria, but few have studied their occurrence and the relationship between the two, such as hypercalciuria in patients with calcium oxalate stones Even with the affected families