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目的了解骨转移瘤患病机体NK活性变化及免疫状况与致命再转移的关系。方法对20例骨转移瘤转输自体LAK前后作了NK活性动态性监测,所测参数与10例正常人作了分析比较。结果正常对照组平均NK活性率（49．5±12．2）％；LAK组治疗前平均NK活性（19.9±20．5）％．治疗后平均活性（35．48±17．44）％．与正常对照组比较差异有显著性（P＜0.05）。结论动态个体NK活性监测用以判断机体免疫状态与疗效较为客观，可作为监测恶瘤再转移的参考指标。
Objective To investigate the changes of NK activity and the relationship between immune status and fatal retransmission in patients with bone metastases. Methods The dynamic changes of NK activity were measured before and after transfusion of autologous LAK in 20 patients with bone metastases. The measured parameters were compared with 10 normal controls. Results The average NK activity rate in the normal control group was (49.5±12.2)%; the average NK activity in the LAK group was (19.9±20.5)%. The average activity after treatment (35.48±17.44)%. Compared with the normal control group, the difference was significant (P<0.05). Conclusion The dynamic individual NK activity monitoring is used to judge the immune status and efficacy of the body. It can be used as a reference index for monitoring the recurrence of malignant tumors.