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从海南产的药用狗牙花Ervatamiaofficinalis中分离并鉴定了9个吲哚生物碱，分别鉴定为12－methoxy－voaphylline（Ⅰ），tabernanthine（Ⅱ），jollyanine（Ⅲ），19，20－dihydro－decarbomethoxyvobasine（Ⅳ），20－epi－19，20－dihydro－decarbomethoxyvobasine（Ⅴ），iboluteine（Ⅵ），conopharyngine（Ⅶ），16′－decarbomethoxy19，20－dihydro－conoduramine（Ⅷ），20－epi－16′－decarbomethoxy19，20-dihydro－conoduramine（Ⅸ）。Ⅴ，Ⅷ和Ⅸ为新生物碱，Ⅷ和Ⅸ经药理实验显示有较强的抗肿瘤作用。
Nine alfalfa alkaloids were isolated and identified from Ervatamiaofficinalis, which was identified in Hainan Province, and identified as 12-methoxy-voaphylline(I), tabernanthine(II), jollyanine(III),19,20-dihydro- Decarbomethoxyvobasine(IV),20-epi-19,20-dihydro-decarbomethoxyvobasine(V),iboluteine(VI),conopharyngine(VII),16′-decarbomethoxy19,20-dihydro-conoduramine(VIII),20-epi-16′ -decarbomethoxy 19,20-dihydro-conoduramine (IX). V, VIII and IX are novel alkaloids, and VIII and IX have been shown to have strong anti-tumor effects through pharmacological experiments.