论文部分内容阅读
目的 :回顾统计分析有病理诊断的结肠息肉 ,更好地认识结肠息肉的临床特点 ,找出与不典型增生息肉相关的因素。方法 :回顾分析镜下切除或钳除的结肠息肉病例共 560例 ,息肉 62 4枚。因变量包括性别、年龄、息肉部位、数目、形态、黏膜情况、是否分叶、病理类型、息肉大小等因素。统计方法包括卡方检验 ,多样本秩和检验 ,spearman等级相关检验 ,逐步logistic分析。结果 :单因素分析显示与不典型增生息肉相关的因素有年龄、息肉大小、黏膜情况、是否分叶状、病理类型。对所有因变量多因素进行逐步logistic分析显示 ,能够独立影响应变量的因变量有年龄、黏膜情况和病理类型。当因变量不包括息肉形态 ,黏膜情况及是否分叶时 ,能够独立影响应变量的因变量有年龄、病理类型和息肉大小。结论 :黏膜有糜烂甚至溃疡、年龄越大、息肉分叶 ,则息肉发生不典型增生的可能性越大。病理为炎性、幼年性、增生性或错构性息肉 ,则息肉发生不典型增生的可能性小。当因变量不包括息肉形态 ,黏膜情况及是否分叶时 ,息肉越大发生不典型增生的可能性越大。
Objective: To review the statistical analysis of pathological diagnosis of colon polyps, to better understand the clinical features of colon polyps, to find out the factors associated with dysplasia polyps. Methods: A total of 560 cases of colon polyps underwent microsurgical resection or forceps removal and 62 4 polyps were retrospectively analyzed. The dependent variables include gender, age, polyp site, number, morphology, mucosa, whether the leaves, pathological type, polyp size and other factors. Statistical methods include chi-square test, multiple sample rank sum test, spearman rank correlation test, stepwise logistic analysis. Results: Univariate analysis showed that the factors associated with atypical hyperplastic polyps were age, polyp size, mucosa status, lobulated status and pathological type. The stepwise logistic analysis of all the multivariate variables showed that the dependent variables that can independently influence the dependent variables were age, mucosal status and pathological type. When dependent variables do not include polyp morphology, mucosal conditions and whether the leaves, independent variables can affect the dependent variables of age, pathological type and polyp size. Conclusion: mucosal erosion or even ulcer, the older, polypoid leaves, the polyp more likely to have atypical hyperplasia. Pathological inflammation, juvenile, hyperplastic or misconstructed polyps, polyps less likely to have atypical hyperplasia. When dependent variables do not include polyp morphology, mucosal conditions and whether the leaves, the greater the possibility of polyps greater atypical hyperplasia.