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From June to September 1998, we selected Opuntia dillenii tablet (ODT) made from Opuntia dillenii Haw, to make a four-week clinical observation on thirty type 2 diabetes mellitus (DM) patients. The study proved that this medicine could improve the glycometabolism of DM patients effectively and avoid the early impairment of renal function of diabetic neuropathy, and it is reported as follows.