1960～1964年我们测定了31例肾阳虚病人,发现其尿17羟皮质类固醇含量均低下,对ACTH试验大多数为延迟反应,初步说明肾阳虚病人有垂体-肾上腺皮质系统的兴奋性低下,由于脑下垂体还受制于更高的中枢,为了进一步探索肾阳虚病人的垂体肾上腺皮质系统低下的原因,于1965年采用了对于下丘脑-垂体-肾上腺皮质系统作全面功能检查的三套测定,即ACTH试验、Su-4885试验、血11羟昼夜节律测定。 From 1960 to 1964, we measured 31 patients with kidney-yang deficiency and found that their urinary 17-hydroxycorticosteroid content was low, and most of the ACTH tests were delayed. It was initially demonstrated that patients with kidney-yang deficiency have hypopituitar-adrenocortical system excitability. Since the pituitary gland is also constrained by a higher center, in order to further explore the causes of hypopituitarism of the pituitary gland in patients with kidney-yang deficiency, three sets of comprehensive functional tests for the hypothalamus-pituitary-adrenocortical system were performed in 1965. Assays: ACTH test, Su-4885 test, and 11-hydroxyl blood circadian rhythm measurement.