The Association between Outdoor Ambient Temperature and the Risk of Low Birth Weight: A Population-B

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Low birth weight (LBW) is defined as a birth weight of less than 2,500 g. It has been estimated that 15%–20% of infants (more than 20 million worldwide) were born with LBW, and 95.6% of the overall LBW infants were born in low and middle income countries[1]. Not only is LBW a crucial cause of infant mortality and morbidity, it also plays a critical role in adverse health outcomes later in life. Therefore, exploring the factors influencing LBW may have important implications for reducing maternal-child health burden.rnIn recent years, the global climate has been undergoing drastic changes. Pregnant women are susceptible to extreme temperature due to their hormone-related physiological changes and variations in immunity and mood[2]. Although the risk of LBW in relation to prenatal exposures to temperature has been studied previously, the findings are inconsistent due to heterogeneity in the socio-economic and environmental factors of different regions[3]. Therefore, it is necessary to explore the effects of meteorological conditions on LBW risk in specific regions.
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