,Fast Electrical Detection of Carcinoembryonic Antigen Based on AlGaN/GaN High Electron Mobility Tra

来源 :中国物理快报(英文版) | 被引量 : 0次 | 上传用户:canghaiyuemenglong
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
As one of the most important tumor-associated antigens of colorectal adenocarcinoma,the carcinoembryonic antigen (CEA) threatens human health seriously all over the globe.Fast electrical and highly sensitive detection of the CEA with AlGaN/GaN high electron mobility transistor is demonstrated experimentally.To achieve a low detection limit,the Au-gated sensing area of the sensor is functionalized with a CEA aptamer instead of the corresponding antibody.The proposed aptasensor has successfully detected different concentrations (ranging from 50 picogram/milliliter (pg/ml) to 50nanogram/milliliter (ng/ml)) of CEA and achieved a detection limit as low as 50pg/ml at Vds =0.5 V.The drain-source current shows a clear increase of 11.5 μA under this bias.
其他文献
期刊
@@
为了提高灵敏度和消除交叉轴串扰,提出了一种包括有效的微型杠杆结构的谐振式差分微加速度传感器, 分析了该结构差分检测和消除交叉轴干扰的原理.推导了该设计的理论模型,包括
A hybrid-pumped Nd∶YAG pulse laser with a double-pass two-rod configuration is presented.The focal length of offset lens is particularly studied to compensate
期刊
@@
引言加拿大西部大麦的过剩、低价及高成本促进了以降低成本而保持或提高籽粒品质的研究。该研究的内容包括在成熟早期收获大麦是否能保持品质而降低因风、雨、雹、霜及操作
Metamorphic In0.55Ga0.45P/In0.06Ga0.94As/Ge triple-junction (3J-MM) solar cells are grown on Ge (100) substrates via metal organic chemical vapor deposition.Epi
期刊
@@
期刊
@@
A simple and repeatable method is proposed for fabricating microfluidic channels on polydimethylsiloxane (PDMS) substrates.In the proposed approach,ridge struct
期刊
@@
Zeeman effect at the hyperfine level of the rovibronic ground state of I35Cl are determined on the basis of |I1JF1I2FMF) via an effective Hamiltonian matrix dia
期刊
@@
期刊
@@
Predicting and modeling of items popularity on web 2.0 have attracted great attention of many scholars.From the perspective of information competition,we propos
期刊
@@