This paper presents the results from unidirectional shaking table tests of two reduced scale steel models of a building frame, with one and two floors, respectively. These frames incorporate friction dissipators at every floor. The inputs are sine-dwells and artificial and registered earthquakes. This study is part of a larger research project aiming to assess the seismic efficiency of friction dissipators by means of an integrated numerical and experimental approach. Inside this framework, the main objectives of these experiments are to: (i) collect a wide range of results to calibrate a numerical model derived within the project, (ii) clarify some of the most controversial issues about friction dissipators (including behavior for inputs containing pulses, capacity to reduce resonance peaks, introduction of high frequencies in the response, and self-generated eccentricities), (iii) better understand their dynamic behavior, (iv) provide insight on the feasibility and reliability of using simple friction dissipators for seismic protection of building structures and (v) characterize the hysteretic behavior of these devices. Most of these objectives are satisfactorily reached and relevant conclusions are stated. This paper presents the results from unidirectional shaking table tests of two reduced scale steel models of a building frame, with one and two floors, respectively. These frames incorporate friction dissipators at every floor. The inputs are sine-dwells and artificial and registered earthquakes. This study is part of a larger research project aiming to assess the seismic efficiency of friction dissipators by means of an integrated numerical and experimental approach. Inside this framework, the main objectives of these experiments are to: (i) collect a wide range of results to calibrate a numerical model derived within the project, (ii) clarify some of the most controversial issues about friction dissipators (including behavior for inputs containing pulses, capacity to reduce resonance peaks, introduction of high frequencies in the response, and self-generated eccentricities ), (iii) better understand their dynamic behavior, (iv) provide insight on the feasibility and reliability of usi ng simple friction dissipators for seismic protection of building structures and (v) characterize the hysteretic behavior of these devices. Most of these objectives are satisfactorily reached and relevant conclusions are stated.