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13三体(Patau’s综合征)患者的生存很少有超过1岁的。Taylor(1968)根据74例得出平均生存期为89.2天。Magenis等(1968)评述了来自不同来源的178例原发的13三体,发现了86％的病例死于1岁以内。已报告生存5岁以上的只是几个个别的例子,而且无一人能在一种以上组织中排除患者不是嵌合体。作者们报告一例男孩,现已9岁,用血和皮肤组织证明为原发的13三体。1969年当这一小孩6天时,做了第一次外周血研究,那时染色体分析显示出大量的细胞计数为
Patients with trisomy 13 (Patau’s syndrome) rarely survive more than 1 year of age. Taylor (1968) based on 74 cases, the average survival was 89.2 days. Magenis et al. (1968) reviewed 178 primary trisomy bodies from 178 different origin and found 86% of the cases died within 1 year of age. It has been reported that there are only a few individual cases of survival over the age of 5, and none of them can exclude patients from being chimerism in more than one type of tissue. The authors report that a boy, now 9 years old, has proven trisomy 13 with blood and skin tissue. The first peripheral blood study was done in 1969 when the child was six days old, when chromosome analysis showed a large number of cells as