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背景:人们对输血相关的庚型肝炎病毒(HGV)感染及其与肝病的关系至今缺乏充分的认识。方法:作者收集了1972年至1995年间357名输血受者,157名没有接受过输血的对照者,500例随机选择的志愿供血者以及230例供血者,后者接受了感染HGV病人的血液经聚合酶链反应检测为HGV RNA阳性,81例输血相关的非甲非乙型肝炎的受者中,79例在输血前后分别收集血清样本进行检测。结果:在79例患有输血相关的肝炎患者中,63例(80％)感染了丙型肝炎病毒(HCV),其中3例输血前有HCV感染,急性肝炎的原因不能被确定。在余下的13例患者中,3例患有急性HGV感染和10例由不明物质引起感染。在63例HCV感染患者
BACKGROUND: There is a lack of full understanding of the relationship between transfusion-related hepatitis G virus (HGV) infection and liver disease. METHODS: The authors collected 357 blood transfusions, 157 untreated controls, 500 randomly selected volunteer donors and 230 donors from 1972 to 1995 who received blood from HGV-infected patients Polymerase chain reaction was positive for HGV RNA. Of the 81 recipients of blood transfusion-associated non-A, non-B hepatitis, 79 were collected before and after transfusion for serum samples. Results: Of the 79 patients with transfusion-related hepatitis, 63 (80%) were infected with hepatitis C virus (HCV), of which 3 had HCV infection before transfusion and the cause of acute hepatitis could not be determined. Of the remaining 13 patients, 3 had an acute HGV infection and 10 had an unknown substance. In 63 patients with HCV infection