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促红细胞生成素 (Ｅｐｏ)是调节红细胞生成的主要激素。类风湿性关节炎 (ＲＡ)伴慢性疾病性贫血 (ＡＣＤ)患者血中Ｅｐｏ水平 ,相对于其贫血程度而言是偏低的[1] 。我们以人肝癌细胞株ＨｅｐＧ2 为模型 ,观察肿瘤坏死因子α(ＴＮＦα)、干扰素 (ＩＦＮ -γ)对钴盐诱导的Ｅｐｏ
Epo (erythropoietin) is a major hormone that regulates erythropoiesis. Epo levels in rheumatoid arthritis (RA) patients with chronic disease-associated anemia (ACD) are low relative to their anemia [1]. We use human hepatocellular carcinoma cell line HepG2 as a model to observe the effects of tumor necrosis factor α (TNFα), interferon (IFN-γ) on cobalt salt-induced Epo