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本文报告了高原婴幼儿重症肺炎并多器官功能衰竭(MOF)42例临床分析。其结果表明:器官衰竭数目与病死率成正比。MOF累及2个器官的最多(61.90％),3个器官的占第二位(28.50％)。前者以心+肺最多(23例),后者以心+肺+脑为多(5例)。其总病死率为45.24％,较刘振寰报告的26.88％显著增高(t=2.0513,P<0.05),其中累及3个或3个以上的器官的病死率分别为75％和100％;年龄越小,累及器官越多,合并症越多(高原心脏病、营养不良等),其病死率越高。本文探讨了MOF的早期诊断及其高原特点。关于MOF的概念提出了建议,阐述了MOF发生先兆,把握其先兆,对于早期诊断,防治MOF,提高其治愈率,降低其发病率具有重要的临床意义。在治疗措施方面,强调在综合治疗的同时,早期改善微循环障碍至关重要。本文介绍了采用654一2治疗重症肺炎并MOF的体会。
This article reports 42 cases of severe pneumonia and multiple organ failure (MOF) in infants and young children at high altitude. The results show that: the number of organ failure and mortality is proportional to. MOF involved two organs (61.90%) and three organs (28.50%). The former with heart + lung up (23 cases), the latter with heart + lung + brain as more (5 cases). The overall case fatality rate was 45.24%, which was significantly higher than that reported by Liu Zhenhuan (26.88%) (t = 2.0513, P <0.05). The case fatality rates of three or more organs were 75% and 100% , Involving more organs, more complications (high altitude heart disease, malnutrition, etc.), the higher the case fatality rate. This article explores the early diagnosis of MOF and its plateau characteristics. The concept of MOF is put forward. It expounds the aura of MOF and its aura. It has important clinical significance for early diagnosis, prevention and treatment of MOF, improvement of its cure rate and reduction of its morbidity. In terms of treatment measures, it is emphasized that while comprehensive treatment, it is very important to improve microcirculation in the early stage. This article describes the use of 654-2 treatment of severe pneumonia and MOF experience.