Amrinone是一种新合成的双吡啶衍生物,动物实验显示有正性收缩能作用。在严重充血性心力衰竭患者,静脉注射Amrinone能增加心排出量和降低左心室充盈压,心功能的改善不伴有心率和动脉压的变化,且无心律失常出现。本文报告10例慢性充血性心力衰竭住院患者口服Amrinone 50～300毫克后对血液动力学和肾功能的临床效果。 Amrinone is a newly synthesized bispyridine derivative that has been shown to show positive contractility by animal experiments. In patients with severe congestive heart failure, intravenous Amrinone can increase cardiac output and reduce left ventricular filling pressure, heart function improvement is not associated with heart rate and arterial pressure changes, and no arrhythmia. This paper reports 10 patients with chronic congestive heart failure inpatients Amrinone oral administration of 50 ~ 300 mg on hemodynamics and renal function after the clinical effect.