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早在20年代,Mac Wieeiaxus和wiggers首先发现—种类似于室颤的心律紊乱,称之为“假性室颤”,此后又有学者称为“短暂性室颤”、“室颤前室速”,1966年,法国学者Desserfenne在研究心室颤动时,发现一种介于室性心动过速和心室颤动之间的心律失常,常能自行终止,该氏对其心电图及临床表现作了系统分析,根据其特异的形态,命名为扭转型室性心动过速(Torsades de pointes下称TDP)。1976年,国内开始有报道,近年来,随着各种病因所致TDP的报道日益增多,对其病因、发病机理及治疗方面都有较大进展。 病因 除了早年报道的一些常见病因外,近几年来几乎每年都有一些新药可引起TDP,常见的病因如下:
As early as the 1920s, Mac Wieeiaxus and Wiggers first discovered - a heart rhythm disorder similar to ventricular fibrillation called “pseudo-ventricular fibrillation,” followed by others known as “transient ventricular fibrillation,” “ventricular tachycardia ”In 1966, the French scholar Desserfenne in the study of ventricular fibrillation, found a ventricular arrhythmia between ventricular tachycardia and ventricular fibrillation, often able to terminate itself, the scholar’s ECG and clinical manifestations were systematically analyzed , According to its specific morphology, named torsades de pointes (Torsades de pointes TDP). In 1976, there are reports in China. In recent years, with the increasing number of reports of TDP caused by various causes, great progress has been made on its etiology, pathogenesis and treatment. In addition to some of the common causes of early reported in recent years, almost every year in recent years, some new drugs can cause TDP, the common causes are as follows: