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目的:考察注射用头孢地嗪钠与5种输液配伍的稳定性。方法:在25℃将头孢地嗪钠分别与0.9%氯化钠注射液、5%葡萄糖注射液、葡萄糖氯化钠注射液、复方氯化钠注射液、木糖醇注射液配伍,在24h内观察配伍液的外观、pH,用高效液相色谱法测定头孢地嗪钠的含量。结果:头孢地嗪钠与5种输液配伍24h内含量大于96%,pH、溶液外观无明显变化。结论:头孢地嗪钠与5种输液在25℃、24h内配伍稳定。
OBJECTIVE: To investigate the stability of cefodizime sodium injection in combination with 5 kinds of transfusion. Methods: Cefodizime sodium was mixed with 0.9% sodium chloride injection, 5% glucose injection, glucose and sodium chloride injection, compound sodium chloride injection and xylitol injection respectively at 25 ℃. Observe the appearance of the compatibility solution, pH, determination of cefodizime sodium content by high performance liquid chromatography. Results: The contents of cefodizime sodium and five kinds of transfusion in 24h were more than 96%, pH, the appearance of the solution had no obvious change. Conclusion: Cefodizime sodium and five kinds of infusion at 25 ℃, 24h compatibility stability.