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目的探讨脐血胆红素水平在预测新生儿黄疸中的应用价值。方法选取2013年1月-2015年1月医院足月新生儿132例。于出生时、出生后24、48、72h测定脐血胆红素水平,并按浓度分为<30μmol/L、≥30μmol/L、≥36μmol/L、≥42μmol/L 4组。所有新生儿均于出生时、生后24、48、72h测定经皮胆红素(测定新生儿前额及前胸2个部位,读数取平均值后记录),比较高胆红素症与非高胆红素血症组的脐血胆红素水平及不同脐血胆红素水平组高胆红素症发生率。结果新生儿脐血胆红素<30μmol/L组黄疸发生率为16.7%明显低于≥30μmol/L组的34.2%、≥36μmol/L组的73.3%及≥45μmol/L组的85.0%,比较差异均有统计学意义(P<0.05)。非高胆红素组脐血胆红素、出生后24、48、72h经皮胆红素指数均低于高胆红素组,比较差异均有统计学意义(P<0.05)。结论高胆红素血症新生儿的脐血胆红素相应升高,测定脐血胆红素对预测新生儿黄疸有实际的应用价值。
Objective To investigate the value of umbilical blood bilirubin in predicting neonatal jaundice. Methods From January 2013 to January 2015, 132 full-term newborns in the hospital were selected. Umbilical blood bilirubin levels were measured at birth, 24,48,72h after birth and divided into 4 groups according to the concentration of <30μmol / L, ≥30μmol / L, ≥36μmol / L, ≥42μmol / L. All newborns were measured at birth, 24,48,72 h after birth transcutaneous bilirubin (determination of neonatal forehead and chest two sites, the average readings were recorded), compared with high bilirubin and non-high The levels of umbilical bilirubin in bilirubin and the incidence of hyperbilirubin in different umbilical bilirubin levels. Results The incidence of jaundice in neonates with umbilical cord bilirubin <30μmol / L was significantly lower than that in the group of ≥30μmol / L 16.7%, 73.3% of ≥36μmol / L and 85.0% of ≥45μmol / L. The differences were statistically significant (P <0.05). In non-hyperbilirubine group, umbilical bilirubin, transdermal bilirubin index at 24, 48 and 72h after birth were all lower than those in hyperbilirubin group (P <0.05). Conclusion Hyperbilirubinemia neonatal umbilical cord blood bilirubin corresponding increase in determination of umbilical cord serum bilirubin in predicting neonatal jaundice has practical value.