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目的探讨男性乳腺癌的治疗和影响预后的主要因素。方法回顾性总结６２例男性乳腺癌的临床特点和治疗方法，分析影响其预后的主要因素。结果男性乳腺癌患者总的５年生存率为６４．５％，根治术与改良根治术患者５年生存率分别为７５．９％和７２．７％，非根治术患者５年生存率为５２．６％（Ｐ＜０．０５），腋窝淋巴结转移率为５６．３％。男性乳腺癌比女性乳腺癌更具有激素依赖性，容易发生腋窝淋巴结转移，预后较差。结论男性乳腺癌患者的治疗首选改良根治术并根据其不同情况辅以放疗、化疗和内分泌治疗，以内分泌治疗为主的综合治疗对晚期患者具有较好的缓解作用。
Objective To explore the treatment of male breast cancer and the main factors that influence the prognosis. Methods The clinical features and treatment of 62 male breast cancers were retrospectively reviewed, and the main factors influencing their prognosis were analyzed. Results The total 5-year survival rate of male breast cancer patients was 64.5%. The 5-year survival rates of radical mastectomy and modified radical mastectomy were 75.9% and 72.7%, respectively. The 5-year survival rate of non radical patients was 52. 6% (P <0.05). Axillary lymph node metastasis rate was 56.3%. Male breast cancer is more hormone-dependent than female breast cancer and is prone to axillary lymph node metastasis, with a poor prognosis. Conclusion The treatment of male breast cancer patients is the first choice of modified radical mastectomy and supplemented by radiotherapy, chemotherapy and endocrine therapy according to their different conditions. Comprehensive treatment based on endocrine therapy has a good alleviation effect on advanced patients.