消炎痛是一种合成的前列腺素抑制剂,过去用于治疗痛风性关节炎、骨关节炎、癌症发热及其它不易控制的发热。近年来发现其生化作用与阿司匹林相同,可能是通过某种酶系统抑制前列腺素酶(PGH_2)的合成,于是临床上有了新的治疗用途。经临床使用证明,消炎痛的副作用较多,发生率竟高达35～50%,故必须引起注意。一、过敏反应服药后可引起口周、舌和四肢麻木,突然心里难受、头痛恶心,语言不利,全身颤动、不能自控,甚至晕倒。有的发生全身血管性浮肿、皮疹。极少数病人有哮喘样发作。过敏反应多于服药后1～2小时出 Indomethacin is a synthetic prostaglandin inhibitor used to treat gouty arthritis, osteoarthritis, cancer fever and other uncontrollable fever. In recent years, it was found that its biochemical effects were the same as those of aspirin, which may be due to inhibition of the synthesis of prostaglandinase (PGH_2) by an enzyme system. Therefore, there is a new therapeutic use in clinic. Proved by clinical use, more side effects of indomethacin, the incidence was as high as 35 to 50%, it must attract attention. First, the allergic reaction can cause perioral, tongue and limb numbness after taking medicine, suddenly my heart uncomfortable, headache nausea, language disadvantage, body vibration, can not be controlled, and even fainted. Some systemic vascular edema, rash. Very few patients have an asthma-like attack. Allergic reactions than taking 1 to 2 hours after taking out