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目的:分析辛伐他汀在颈动脉粥样硬化治疗中的应用效果。方法:选择我院2009年10月—2010年9月收治的颈动脉粥样硬化102例按照随机数字表法分为两组,对照组51例采用常规治疗,观察组51例在对照组的基础上加用辛伐他汀治疗,对两组的临床治疗情况进行观察比较。结果:治疗后两组患者的颈总动脉内膜-中层厚度(IMT)、斑块面积明显缩小,观察组变化更明显,组间差异有统计学意义(P<0.05);两组患者治疗过程中均无严重不良反应发生。结论:辛伐他汀在颈动脉粥样硬化治疗中的应用效果满意,且无严重不良反应发生,安全性好,值得临床关注。
Objective: To analyze the effect of simvastatin in the treatment of carotid atherosclerosis. Methods: A total of 102 cases of carotid atherosclerosis admitted to our hospital from October 2009 to September 2010 were divided into two groups according to the random number table. 51 cases in the control group were treated routinely. The observation group consisted of 51 cases in the control group On the plus simvastatin treatment, the clinical treatment of the two groups were observed and compared. Results: The intima-media thickness (IMT) and plaque area of common carotid arteries in both groups were significantly reduced after treatment, and the changes in the observation group were more obvious with statistical significance (P <0.05). The treatment course No serious adverse reactions occurred. Conclusion: The effect of simvastatin in the treatment of carotid atherosclerosis is satisfactory, and no serious adverse reactions, safety, and worthy of clinical attention.