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胰岛素样生长因子Ⅱ（ＩＧＦⅡ）和转化生长因子α（ＴＧＦα）都是肝细胞癌时的增殖因子，在癌组织中肝细胞能大量表达这两种细胞因子及其受体［１］。本文应用放射免疫分析法检测了肝癌和肝硬化患者血清中ＩＧＦⅡ和ＴＧＦα的水平，并分析了其与甲胎蛋白（ＡＦＰ）
Insulin-like growth factor-II (IGF-II) and transforming growth factor-alpha (TGF-alpha) are both proliferation factors in hepatocellular carcinoma. Hepatocytes can express a large number of these cytokines and their receptors in cancer tissues [1 ]. The levels of IGF-II and TGF-α in the serum of patients with hepatocellular carcinoma and liver cirrhosis were detected by radioimmunoassay and analyzed with alpha-fetoprotein (AFP).