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目的提高子宫颈癌前期病变及宫颈癌的检出率,降低宫颈癌的发病率。方法2007年1～12月对在丽水市妇幼保健院进行妇科检查的16451例女性随机抽取两组,开展Thinprep液基细胞学(TCT)检查和传统巴氏涂片检查各753例,对检查发现异常的病例均进行阴道镜检查及镜下活组织病理检查。结果TCT检出宫颈异常病变69例,检出率9.16%,传统巴氏涂片检出宫颈异常病变21例,检出率为2.79%,二者差异有统计学意义(P<0.01);TCT检出的69例宫颈病变在阴道镜下活检结果符合率为88.40%(61/69),传统巴氏涂片检出21例宫颈病变在阴道镜下活检结果符合率为66.67%(14/21),二者间差异有统计学意义(P<0.05)。结论TCT新技术是筛查子宫颈癌前病变及宫颈癌的可靠手段。
Objective To improve the detection rate of cervical precancerous lesions and cervical cancer and reduce the incidence of cervical cancer. Methods From January 2007 to December 2007, 16451 women with gynecological examination in Lishui Maternal and Child Health Care Hospital were randomly divided into two groups. Thinprep liquid-based cytology (TCT) and traditional Pap smear were performed in 753 cases. Abnormal cases were colposcopy and microscopic biopsy. Results TCT detected abnormal cervical lesions in 69 cases, the detection rate of 9.16%, 21 cases of cervical papilloma lesions detected by conventional Pap test, the detection rate was 2.79%, the difference was statistically significant (P <0.01); TCT The coincidence rate of colposcopy in 69 cases of cervical lesions detected by colposcopy was 88.40% (61/69). The colposcopy biopsy results of 21 cases of cervical lesions detected by conventional Pap smear were 66.67% (14/21 ), The difference between the two was statistically significant (P <0.05). Conclusion The new TCT technique is a reliable method to screen the precancerous lesions of cervix and cervical cancer.