新型隐球菌脑膜炎(Cryptococcal meningitis CNM)是由新型隐球菌或其变种侵犯中枢神经系统导致的颅内感染。临床主要表现为亚急性或慢性脑膜炎、脑膜脑炎,少数可表现为颅内占位性病变。本病临床特点缺乏特异性,易误诊、误治,病死率及致残率高。近年来随着获得性免疫缺陷病毒(HIV)感染率和艾滋病(AIDS)的发病率上 Cryptococcal meningitis (CNM) is an intracranial infection caused by the invasion of the central nervous system by Cryptococcus neoformans or its variants. The main clinical manifestations of subacute or chronic meningitis, meningoencephalitis, a few may show as intracranial space-occupying lesions. The lack of specificity of clinical features of the disease, misdiagnosis, mistreatment, mortality and disability rate. In recent years, with the prevalence of acquired immunodeficiency virus (HIV) and AIDS (AIDS)