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Objective To study the lung function changes of infants with pneumonia via tidal breathing pattern analysis before and after treatment. Methods Tidal Flow-Volume Loops(TFV) were measured using the tidal breathing pattern in 58 infants (1～40 months old) with pneumonia. Sixty-three normal infants were used as controls. The parameters, including respiratory rate (RR), inspiratory and expiratory time (Ti, Te), the ratio of Ti/Te, peak tidal expiratory flow (PTEF), the ratio of time to reach peak tidal expiratory flow (TPTEF)to total expiratory time (TE), the ratio of volume to reach peak tidal expiratory flow (VPEF) to total expiratory volume (VE), tidal volume per kilogram (VT/kg), mean inspiratory flow (MIF), mean expiratory flow (MEF), and tidal expiratory flow at 25%, 50%,75% lung volume(TEF 25%, TEF 50% and TEF 75%) were measured using the Masterscreen-Paediatric (a tool for the lung function test). Results RR increased, TPTEF, TPTEF/TE, VPEF, VPEF/VE were lower in infants with pneumonia compared with those ofthe controls [RR= (36±9)/min vs (30±8)/ min, TPTEF= ( 0.20± 0.08) s vs ( 0.40± 0.16) s, TPTEF/TE=( 18.8± 5.8)% vs ( 33.0± 7.5)%, VPEF=( 17.2± 10.9) ml vs ( 25.4± 12.8) ml, VPEF/VE=( 22.1± 4.6)% vs ( 33.4± 6.35)%](P< 0.01). TI,TE, TI/TE were shortened. It appeared that the airway was obstructive. After the routine therapy, RR decreased to (33±11)/min, TPTEF/TE and VPEF/TE were significantly higher [( 26.2± 8.7) and ( 8.4± 7.3)% , respectively](P< 0.01). Conclusions Tidal breathing pattern can be used to evaluate the lung function and the effect of therapy in infants with pneumonia.
Objective To study the lung function changes of infants with pneumonia via tidal breathing pattern analysis before and after treatment. Methods Tidal Flow-Volume Loops (TFV) were measured using the tidal breathing pattern in 58 infants (1 ~ 40 months old) with pneumonia. The parameters, including respiratory rate (RR), inspiratory and expiratory time (Ti, Te), the ratio of Ti / Te, peak tidal expiratory flow (PTEF), the ratio of time to reach peak tidal expiratory flow (TPTEF) to total expiratory time (TE), the ratio of volume to reach peak tidal expiratory flow (VPEF) to total expiratory volume (VE), tidal volume per kilogram (VT / kg) (MEF), and tidal expiratory flow at 25%, 50%, 75% lung volume (TEF 25%, TEF 50% and TEF 75%) were measured using the Masterscreen- Pediatric (a tool for the lung function test. Results RR increased, TPTEF, TPTEF / TE, VPEF, VPEF / VE were lower in infants with p neumonia compared with those of the controls [RR = (36 ± 9) / min vs (30 ± 8) / min, TPTEF = (0.20 ± 0.08) s vs (0.40 ± 0.16) s, TPTEF / TE = (18.8 ± 5.8) VPEF / VE was (22.1 ± 4.6)% vs (33.4 ± 6.35)%] (P <0.01) .Conclusion: It was that the airway was obstructive. After the routine therapy, RR decreased to (33 ± 11) / min, TPTEF / TE and VPEF / TE were significantly higher [(26.2 ± 8.7) (8.4 ± 7.3)%, respectively] (P <0.01). Conclusions Tidal breathing pattern can be used to evaluate the lung function and the effect of therapy in infants with pneumonia.