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为探讨急性多发性硬化症的临床病理特点及其诊断和鉴别诊断要点，对１０例急性多发性硬化症（ＡＭＳ）尸体解剖病例作了临床病理分析。该病是多发性硬化症中一种少见的致死性类型。患者突出的临床特点为精神异常、瘫痪和大小便失禁。脱髓鞘病变表现为影斑、白质内空泡状病变及软化灶三种形式。其病变可单独存在也可互相移行。确诊本病主要根据上述病理组织学改变。还对ＡＭＳ和急性播散性脑脊髓炎的鉴别要点进行了讨论。
In order to explore the clinicopathological features of acute multiple sclerosis and its diagnostic and differential diagnosis points, 10 cases of acute multiple sclerosis (AMS) autopsy cases were analyzed clinically and pathologically. The disease is a rare type of multiple sclerosis fatal. Outstanding clinical features of patients with mental disorders, paralysis and incontinence. Demyelinating lesions manifested as shadow, white matter vacuolar lesions and three forms of softening lesions. The lesions can exist alone or with each other. The diagnosis of the disease mainly based on the histopathological changes. AMS and acute disseminated encephalomyelitis also identified the main points were discussed.