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目的:回顾分析影响腮腺癌预后的因素,并从放射治疗的角度提出改善腮腺癌预后的措施。资料和方法:复习1979-1989年收治并经病理证实的腮腺癌182例。Ⅰ期47例、Ⅱ期46例、Ⅲ期45例、Ⅳ期44例。单纯手术64例,手术加放疗114例,单纯放疗和化疗各2例。结果:总的5、10年生存率分别为68.1%(124/182)和53.8%(50/93)。肿瘤有疼痛、局部有浸润、Ⅶ颅神经受侵面部有麻木使5、10年生存率下降。术后放疗组的5年和10年生存率比单纯手术组分别提高了16.0%和24.5%(P<0.05)。结论:腮腺癌的治疗应提倡手术加放射的综合治疗,放射治疗剂量≥50Gy者预后比<50Gy者要好,光子束和电子束混合射线照射预后最好;必须强调手术的彻底性。
OBJECTIVE: To retrospectively analyze the factors affecting the prognosis of parotid gland carcinoma and to propose measures to improve the prognosis of parotid gland carcinoma from the perspective of radiotherapy. Materials and Methods: One hundred and eighty-seven cases of parotid gland carcinoma were retrospectively reviewed from 1979 to 1989. 47 cases of stage Ⅰ, 46 cases of stage Ⅱ, 45 cases of stage Ⅲ, 44 cases of stage Ⅳ. 64 cases of simple surgery, surgery plus radiotherapy in 114 cases, radiotherapy alone and chemotherapy in 2 cases. Results: The overall 5-year and 10-year survival rates were 68.1% (124/182) and 53.8% (50/93), respectively. Tumors have pain, local infiltration, â ... ¢ cranial nerve invasion of the face of numbness, 5, 10-year survival rate decreased. The 5-year and 10-year survival rates of postoperative radiotherapy group were increased by 16.0% and 24.5% respectively (P <0.05). Conclusions: The treatment of parotid gland carcinoma should advocate the combination of surgery and radiation. The prognosis of radiotherapy dose ≥50 Gy is better than that of <50 Gy. The prognosis of photon beam and electron beam hybrid beam irradiation is the best. The thoroughness of operation must be emphasized.