本文报告1例原发性血小板增多症患者,在病程中转化为骨髓纤维化(MF),最终转变为急性粒-单核细胞白血病。病历摘要患者女,142岁,住院号204147,因头晕、乏力2年,鼻衄、牙龈出血2月,于1985年5月首次入院。既往史、家族史均无特殊。入院体检:体温37℃,牙龈少量渗血,其余未发现异常。化验:血红蛋白120g/ This article reports one patient with essential thrombocytopenia that is converted to myelofibrosis (MF) during the course of the disease and eventually to acute myelomonocytic leukemia. Medical record Abstract Female patient, 142 years old, hospital number 204147, due to dizziness, fatigue for 2 years, epistaxis, gingival bleeding in February, was first admitted to hospital in May 1985. Past history, family history are no special. Admission examination: body temperature 37 ℃, a small amount of bleeding gums, the rest found no abnormalities. Laboratory tests: hemoglobin 120g /