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先兆流产患者有许多可用于评价妊娠结局的母体血清标记物。近年先兆流产患者血清标记物的研究成为重点,如人绒毛膜促性腺激素、孕激素、雌激素、CA125、抑制素A、激活素A、妊娠相关血浆蛋白A和细胞因子等。对先兆流产患者血清学改变行连续测定可指导治疗、评价疗效及预测不良妊娠结局;可避免盲目保胎造成稽留流产;同时也可避免医源性的资源浪费。先兆流产相关血清学改变的连续测定在其诊断及治疗中有重要临床意义。
Threatened abortion patients have many maternal serum markers that can be used to assess pregnancy outcomes. In recent years, studies of serum markers of threatened abortion have become important, such as human chorionic gonadotropin, progesterone, estrogen, CA125, inhibin A, activin A, pregnancy related plasma protein A and cytokines. Continual determination of serological changes in threatened abortion patients can guide the treatment, evaluation of the efficacy and prediction of adverse pregnancy outcomes; blind miscarriage can lead to missed abortion; but also to avoid iatrogenic waste of resources. Continuous determination of threatened abortion-related serological changes in the diagnosis and treatment of important clinical significance.