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目的 分析不同激素分泌类型垂体腺瘤的临床特点及MRI征象 ,评价其规律性及临床指导价值。方法 收集 1996～2 0 0 0年住院病人中MRI术前诊断及手术、病理证实的垂体腺瘤 2 0 0例 ,按激素分泌类型分别分析其年龄、性别、临床症状、体征 ;MRI上肿瘤大小、形态、信号特点及向周围侵犯情况。结果 垂体腺瘤的发病年龄跨度较大 ,但 3 5～ 5 5岁之间占 60 %。泌乳素腺瘤男女比例为 1∶2 ,黄体生成素腺瘤 12例、促甲状腺激素腺瘤 2例为男性 ,余男女发病率相似。临床症状、体征交叉出现。MRI表现 ,垂体瘤大小从 0 .5cm× 0 .8cm× 1cm～ 6cm× 7cm× 8cm ,多激素腺瘤最大直径多 >5cm。增强前后信号特征无明显差异 ,未见钙化。最多见者为向鞍上生长 ,其次为向下、两侧或一侧海绵窦及第三脑室下部。结论 不同激素分泌类型垂体腺瘤具有一定的临床及MRI特征 ,虽不能据此作出确切的激素分泌类型诊断 ,但在一定程度上可以为临床提供参考
Objective To analyze the clinical features and MRI features of different hormone-secreting pituitary adenomas and evaluate the regularity and clinical value. Methods Totally 200 cases of pituitary adenomas proved by preoperative MRI and pathological examination in inpatients from 1996 to 2000 were collected. Their age, sex, clinical symptoms and signs were analyzed according to the type of hormone secretion. The size of tumor on MRI , Morphology, signal characteristics and the surrounding violations. Results The incidence of pituitary adenoma was larger, but it was 60% between 35 and 55 years old. Prolactinoma of the male to female ratio of 1: 2, 12 cases of luteinizing hormone adenoma, thyroid stimulating adenoma 2 cases of male, more than the incidence of men and women. Clinical symptoms, signs cross appears. MRI showed that the size of pituitary tumor from 0 .5cm × 0 .8cm × 1cm ~ 6cm × 7cm × 8cm, multi-hormone adenoma more than the maximum diameter of> 5cm. Before and after enhancing the signal characteristics no significant difference, no calcification. The most common to the saddle growth, followed by down, both sides or side of the cavernous sinus and the third lower part of the ventricle. Conclusions The different types of hormone secreting pituitary adenomas have certain clinical and MRI features. Although exact diagnosis of hormone secretion type can not be made accordingly, it can provide a reference for clinic to a certain extent