重症急性胰腺炎(severe acute pancreatitis,SAP)近年来发病率呈现升高的趋向,特别是合并多脏器功能不全或衰竭的发病机理尚未完全清楚,其常见的三大器官损害中,肾肺损害能够做到早期诊断及正确治疗,而脑组织损害作用机理极为复杂。胰性脑组织损害(pancreatic brain tissue injury,PBTI)是胰腺炎发病及治疗过程中的严重并发症之一,常发生于反复 The incidence of severe acute pancreatitis (SAP) has been increasing in recent years. In particular, the pathogenesis of combined multiple organ dysfunction or failure is not fully understood. Among the common three major organ damage, renal damage Can do early diagnosis and correct treatment, and brain damage mechanism is extremely complex. Pancreatic brain injury (pancreatic brain tissue injury, PBTI) is one of the serious complications in the pathogenesis and treatment of pancreatitis, which often occurs in repeated