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目的探讨纤维蛋白原、三酰甘油与脑小血管病血管病变的关系。方法选取脑小血管病患者140例组成实验组。另选30例健康患者作为对照组。比较2组患者纤维蛋白原(FIB)、脑动脉脉动指数(PI)、CTT和三酰甘油(TG)水平并分析纤维蛋白原、三酰甘油与脑小血管病(SVD)血管病变的关系和脑小血管病血管病变的危险因素。结果实验组患者纤维蛋白原、三酰甘油水平、脑动脉脉动指数和CTT均较对照组升高,差异有统计学意义(P<0.05)Pearson相关性分析结果显示,FIB、TG与脑小血管病血管病变程度均呈正相关(rFIB=6.85,rTG=7.43,P<0.01)。多因素分析结果显示,血压、FIB和TG是脑小血管病血管病变的独立危险因素。结论脑小血管病患者纤维蛋白原和三酰甘油水平升高,纤维蛋白原和三酰甘油与脑小血管病血管病变均呈正相关,血压、纤维蛋白原和三酰甘油是脑小血管病血管病变的独立危险因素。
Objective To investigate the relationship between fibrinogen, triglyceride and vascular lesion of cerebral vascular disease. Methods Selected 140 patients with cerebral vascular disease composed of experimental group. Another 30 healthy patients as a control group. The fibrinogen (FIB), cerebral arterial pulse index (PI), CTT and triglyceride (TG) levels were compared between the two groups and the relationship between fibrinogen, triglyceride and vascular disease of cerebrovascular disease Risk factors for vascular disease of cerebrovascular disease. Results The levels of fibrinogen, triglyceride, arterial pulse index and CTT in experimental group were significantly higher than those in control group (P <0.05). Pearson correlation analysis showed that FIB, TG and cerebral microvascular The degree of vascular disease was positively correlated (rFIB = 6.85, rTG = 7.43, P <0.01). Multivariate analysis showed that blood pressure, FIB and TG were independent risk factors for CVD in patients with cerebrovascular disease. Conclusions Fibrinogen and triglyceride levels are increased in patients with cerebrovascular disease. Fibrinogen and triglyceride are positively correlated with vascular lesions of cerebrovascular disease. Blood pressure, fibrinogen, and triglyceride are the pathogenesis of cerebrovascular disease Independent risk factors for disease.