论文部分内容阅读
促宫颈成熟的最佳方法应具备安全有效、无害无副作用等条件.许多研究证明阴道应用小剂量前列腺素E_2(PGE_2)促宫颈成熟不仅安全可靠,而且降低了催产素的使用率,其原理是PGE_2可以分解宫颈的胶原纤维束,使宫颈软化而扩张,而口服PGE_2不能同宫颈组织内的载体结合故效果不理想.但是目前对于PGE_2阴道用药的最佳剂量和方法尚有争议.本实验采用双盲法比较阴道内放置PaE_2胶冻及药膜两法促宫颈成熟的有效率及副作用. 受试对象69例,为需要引产但宫颈尚未成熟(Bishop’s评分≤4),胎膜完整,胎先露为头,本人自愿接受PGE_2治疗者.用药前行N. S. T监护为
The best method to promote cervical maturity should be safe and effective, harmless and no side effects and many other conditions.Many studies have shown that vaginal application of small doses of prostaglandin E_2 (PGE_2) to promote cervical ripening is not only safe and reliable, but also reduces the rate of oxytocin, the principle PGE_2 can decompose the collagen fibers of the cervix to soften and expand the cervix, but oral PGE_2 can not combine with the carrier in the cervical tissue, so the optimal dose and method for vaginal administration of PGE_2 are still controversial. The double-blind method was used to compare the effectiveness and side effects of intravaginal PaE_2 jelly and drug film in promoting intravaginal maturation.Methods Sixty-nine women were enrolled in this study, who were in need of induction of labor but not yet mature (Bishop’s score ≤4) First exposed, I voluntarily accept PGE_2 treatment