本文报告第一例乳腺结核并发何杰金氏病病例。患者,女,26岁。于1976年(第二次分娩后一年)发现左乳有一包块,伴咳嗽和体重下降。查体提示包块为一脓肿。胸部 X 线示左肺上叶空洞性病变,右肺上叶有一阴影。乳腺包块活检示肉芽肿性乳腺炎,并有广泛干酪样坏死。痰抗酸杆菌染色及结核杆菌培养均阳性。抗结核治疗,临床及 X 线反应良好。左乳患结核8年后,又发现右乳有一软的包块,并有厌食、咳嗽、盗汗和搔痒。查体见右胸骨旁一质软的包块,扩展到肋间软组织。双侧腋窝、颈部和锁骨上淋巴结肿大。右腋淋巴结活检见多形性的网织细胞、RS 细胞和陷窝细胞浸润并有纤维 This article reports the first case of breast tuberculosis complicated with Hodgkin’s disease. The patient, female, is 26 years old. In 1976 (one year after the second delivery), there was a mass of left breast with cough and weight loss. The physical examination revealed that the mass was an abscess. The chest X-ray shows the left upper lobe cavity lesions and the right lung lobe has a shadow. Mammary gland biopsy showed granulomatous mastitis with extensive caseous necrosis. The acid-fast bacillus stain and Mycobacterium tuberculosis culture were positive. Anti-tuberculosis treatment has good clinical and X-ray response. Eight years after left breast tuberculosis, right breast milk was found to have a soft mass, and there was anorexia, cough, night sweats, and itching. The examination showed a soft mass next to the right sternal mass and expanded to the intercostal soft tissue. Bilateral popliteal, neck, and supraclavicular lymph nodes. The right axillary lymph node biopsy showed pleomorphic reticulocytes, RS cells, and cave cell infiltration with fibers