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目的:分析山豆根临床使用时致儿童神经系统不良反应发生的特点和规律。方法:通过讨论1例山豆根致儿童急性小脑性共济失调的临床资料,并检索中国期刊全文数据库和万方数据库,收集2000年1月-2010年12月国内期刊报道收录的山豆根致儿童神经系统不良反应的文献,并进行分析。结果:山豆根致儿童神经系统不良反应主要损害部位为基底节神经核与小脑,主要表现为肌张力障碍与共济失调,部分出现急性脑病表现。结论:山豆根可以引起儿童神经系统不良反应,在儿科的应用时应严格掌握适应证,并注意观察不良反应,保障儿童用药安全。
OBJECTIVE: To analyze the characteristics and regularities of the adverse reactions to the nervous system of children caused by Fructus-Rhynchophylla in clinic. Methods: The clinical data of 1 case of acute cerebellar ataxia caused by shadoung root were studied, and the full-text database of Chinese periodicals and Wanfang database were searched. The collected data of shadoung rooted in domestic journals from January 2000 to December 2010 The literature on the adverse effects of the nervous system in children is analyzed and analyzed. Results: The main damage to the nervous system of children induced by shadoung root was the basal ganglia and cerebellum. The main manifestations were dystonia and ataxia, and some showed acute encephalopathy. Conclusion: Radix solanum can cause adverse reactions of nervous system in children. In pediatric application, indications should be strictly controlled and adverse reactions should be observed to ensure the safety of children.