张××,女,38岁,农民,于1971年初发现肺结核,曾用异烟肼等多种药物治疗无效,于1975年2月25日开始口服利福平(上海第五制药厂制,批号750201),每日剂量450毫克,分3次服,同时合用异烟肼,每日600毫克口服(患者体重35公斤)服后3天,体温逐步下降,第5天,出现食欲减退和恶心呕吐,加用中草药治疗,胃肠症状好转,但至第10天,发现巩膜黄染,肝功能:锌浊度15单位,谷丙转氨酶 Zhang × ×, female, 38 years old, farmer, found tuberculosis in early 1971, had used isoniazid and other drugs ineffective, began on February 25, 1975 oral rifampin (Shanghai Pharmaceutical Factory No. 5, batch number 750,201), a daily dose of 450 mg, divided into 3 doses, while combined with isoniazid, 600 mg daily oral (patient weight 35 kg) serving 3 days after the gradual decline in body temperature on the 5th day, loss of appetite and nausea and vomiting , Plus Chinese herbal medicine treatment, gastrointestinal symptoms improved, but by the 10th day and found scleral yellow dye, liver function: zinc turbidity 15 units, alanine aminotransferase