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目的:探讨比索洛尔引起的不良反应的一般规律及临床特点。方法:对比索洛尔引起不良反应的23例患者的临床资料进行回顾性分析。结果:产生不良反应的患者中,男性多于女性,且多于用药6天后出现不良反应症状;导致不良反应的用药剂量多为2.5~5.0mg/d;不良反应累及心血管系统、神经系统、泌尿系统、呼吸系统、内分泌系统等;所有病例经对症处理或停药后均痊愈,无死亡病例。结论:比索洛尔可引起诸多不良反应,累及多种组织器官,且存在明显性别差异,临床应给予高度重视。
Objective: To investigate the general rules and clinical features of bisoprolol-induced adverse reactions. Methods: A retrospective analysis was performed on the clinical data of 23 patients with adverse reactions caused by Sorolol. Results: There were more males than females and more adverse reactions than those of females after 6 days of treatment. The dose of adverse reactions was mostly 2.5-5.0 mg / d. The adverse reactions involved cardiovascular system, nervous system, Urinary system, respiratory system, endocrine system, etc .; all cases were cured or stopped after symptomatic treatment, no deaths. Conclusion: Bisoprolol can cause a lot of adverse reactions, involving a variety of tissues and organs, and there are significant gender differences, clinical should be given high priority.