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对胃溃疡、胃癌患者胃窦粘膜生长抑素含量变化进行研究 ,分析了胃溃疡、胃癌患者胃窦粘膜生长抑素含量变化的意义。结果显示 :胃溃疡组胃窦粘膜生长抑素 (SS)含量低于对照组 (P <0 .0 5)及胃癌组 (P <0 .0 1 ) ,而胃癌组SS含量均显著高于其它组 (P均 <0 .0 1 )。胃窦粘膜中SS含量变化可能在胃溃疡、胃癌的发病机理中起重要作用 ,胃窦粘膜SS含量显著升高可能成为早期胃癌的辅助诊断指标。
To study the changes of somatostatin contents in antral gastric mucosa of patients with gastric ulcer and gastric cancer, and to analyze the significance of the change of somatostatin content in antral gastric mucosa of patients with gastric ulcer and gastric cancer. The results showed that gastric mucosal somatostatin (SS) content in gastric ulcer group was lower than that in control group (P <0.05) and gastric cancer group (P <0.01), while SS content in gastric cancer group was significantly higher than other groups Group (all P <0.01). The change of SS content in gastric mucosa may play an important role in the pathogenesis of gastric ulcer and gastric cancer. The significant increase of SS in gastric mucosa may be an auxiliary diagnostic indicator of early gastric cancer.