论文部分内容阅读
胃食管反流病(GERD)是指胃内容物反流入食管,引起不适症状和(或)并发症的一种疾病。根据内镜和病理结果可将GERD分为三类:(1)反流性食管炎(RE):有反流症状兼有食管黏膜破损者;(2)非糜烂性食管反流病(NERD):有反流症状但内镜下未见食管破损者;(3)Barrett食管(BE):食管黏膜上皮被胃柱状上皮所替代。GERD为常见的慢性疾病,易反复发作,严重影响患者的生活质量,造成沉重的经济和社会负担。本文就该病的发病机制、诊断及治疗进展做一简要综述。
Gastroesophageal reflux disease (GERD) is a disease in which gastric contents reflux into the esophagus, causing symptoms and / or complications. According to endoscopic and pathological findings, GERD can be divided into three categories: (1) reflux esophagitis (RE): both reflux symptoms and esophageal mucosal damage; (2) non-erosive esophageal reflux disease (NERD) : Reflux symptoms but no endoscopic esophageal damage; (3) Barrett’s esophagus (BE): esophageal epithelium was replaced by gastric columnar epithelium. GERD is a common chronic disease, easy to repeated attacks, seriously affecting the quality of life of patients, causing heavy economic and social burden. This article gives a brief overview of the pathogenesis, diagnosis and treatment of the disease.