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目的了解苍南地区宫颈疾病的筛查现状和宫颈癌前病变(CIN)及宫颈癌的发病情况,并对病变患者进行早期干预。方法对2010年6月-2012年6月苍南地区符合筛查条件的10 234名妇女进行子宫颈脱落细胞学检查,细胞学检查可疑者进行高危型人乳头瘤病毒(HR-HPV)的检测及阴道镜检查。对异常者取组织做病理检查。对宫颈病变确立患病进行跟踪随访和指导规范治疗,做TCT检查、HPV检查及手术治疗后相关指标复查,动态观察早干预对宫颈癌前病变及宫颈癌预后的影响。结果 10 234名妇女中筛查中发现宫颈脱落细胞学异常187人,异常发现率为1.83%,病理诊断宫颈癌9人,发病率为0.09%,癌前病变患者有80人0.78%。对宫颈病变确立患病进行跟踪随访和指导规范治疗后,80例宫颈癌前病变患者中65例逆转,逆转率81.25%,持续12人,持续率为15.00%,发展3人,发展率为3.75%,9例宫颈癌患者经手术治疗后,随访半年,患者恢复良好,无1例死亡。结论选择有效的方法对宫颈疾病进行筛查,并对宫颈病变的患者进行早期干预治疗及随访,对宫颈癌的防治有重要的意义。
Objective To investigate the screening status of cervical diseases and the incidence of cervical precancerous lesions (CIN) and cervical cancer in Cangnan and to make early intervention in patients with lesions. Methods A total of 10 234 women eligible for screening in Cangnan from June 2010 to June 2012 underwent cervical cytology examination. Cytological examination of suspicious individuals was performed to detect high-risk human papillomavirus (HR-HPV) Colposcopy. Abnormal tissue taken for pathological examination. The pathological changes of cervical lesions established follow-up and guide the standard treatment, do TCT examination, HPV examination and review of relevant indicators after surgery, dynamic observation of early intervention on cervical precancerous lesions and cervical cancer prognosis. Results A total of 187 cervical cytology abnormalities were found in 10 234 women. The abnormality rate was 1.83%. The pathological diagnosis of cervical cancer was 9, the incidence rate was 0.09%, and the incidence of precancerous lesions was 0.78%. Of the 80 cases of cervical precancerous lesions in 65 cases of reversal, the reversal rate of 81.25%, for 12 people, the sustained rate was 15.00%, the development of 3 people, the development rate was 3.75 %, 9 cases of cervical cancer patients after surgery, followed up for six months, the patient recovered well, no one died. Conclusion The effective method of cervical screening screening, and cervical lesions in patients with early intervention and follow-up, prevention and treatment of cervical cancer is important.