论文部分内容阅读
目的了解福建省武平县1988-1999年出生人群中A群、C群流行性脑脊髓膜炎(简称流脑)的免疫状况。方法采用分层随机抽样方法,采集1988—1999年出生人群血清标本271份,用ELISA法检测流脑A群、C群IgG抗体水平。结果 A群、C群流脑抗体阳性率分别为86.3%和1.5%,不同年龄组和性别的A群、C群流脑抗体水平类似,既往免疫规划工作好与差的乡镇间,A群流脑抗体水平差异有显著性。结论武平县1988-1999年出生人群对A群流脑具有较高免疫力,但对C群流脑几乎无免疫力,建议适当扩大A+C群流脑疫苗接种的年龄范围,提高重点人群的免疫力。
Objective To understand the immune status of group A and group C meningococcal meningitis (referred to as meningitis) in Wuping County of Fujian Province from 1988 to 1999. Methods A total of 271 serum samples from 1988 to 1999 were collected by stratified random sampling method. The levels of IgG antibodies in meningococcal group A and C were detected by ELISA. Results The positive rates of meningococcal antibody in group A and group C were 86.3% and 1.5%, respectively. The antibody levels of group A and group C were similar in different age groups and sexes. The previous immunization program was good and poor, Differences in brain antibody levels were significant. Conclusion The population born in 1988-1999 in Wuping County is highly immune to the meningitis A group but has no immunity to the group C meningitis. It is suggested that the age range of meningococcal vaccination should be appropriately extended to increase the Immune.