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目的:探讨丙泊酚联合米非司酮在绝经后妇女取环中的应用价值。方法:对我院2007年6月至2009年6月期间124例绝经后取环妇女进行回顾性分析,分为两组,每组62例。观察组予米非司酮25mg、口服、1次/12h、共3天,第4天术前禁食6h,行丙泊酚静脉麻醉、无痛取环;对照组在丙泊酚静脉麻醉后常规宫颈注射1%利多卡因2ml,观察两组宫颈软化、手术时间、出血量及成功率。结果:观察组;宫颈软化率82.26%,手术时间<5min者占77.42%,出血量(2.0±0.7)ml,一次性取环成功率100%。对照组:宫颈软化率9.68%,手术时间<5min者占17.74%,出血量(3.6±0.9)ml,一次性取环成功率85.48%,两组比较有显著差异。结论:丙泊酚联合米非司酮用于绝经后妇女取环安全、可靠,值得临床推广。
Objective: To investigate the value of propofol combined with mifepristone in the postmenopausal women. Methods: A retrospective analysis of 124 cases of postmenopausal women in our hospital from June 2007 to June 2009 were divided into two groups, 62 cases in each group. The observation group was treated with mifepristone 25mg, orally, once / 12h for 3 days. On the 4th day, the rats were fasted for 6h before anesthesia with propofol and without pain. The patients in the control group were anesthetized with propofol Conventional cervical injection of 1% lidocaine 2ml, observed two groups of cervical softening, operation time, bleeding and success rate. Results: In the observation group, the rate of cervical softening was 82.26%, the operation time was less than 5 minutes and the rate of bleeding was (2.0 ± 0.7) ml and 77% respectively. In the control group, the rate of cervical softening was 9.68%, the operation time was less than 5 minutes, the volume of bleeding was (3.6 ± 0.9) ml and the rate of one-time loop was 85.48%. There were significant differences between the two groups. Conclusion: Propofol combined with mifepristone is safe and reliable for postmenopausal women, which is worthy of clinical promotion.