牛磺酸生物学作用广泛,具有修复血管内皮功能、抗脂质过氧化、减轻细胞钙超载、抑制血管平滑肌细胞增殖、抑制细胞凋亡、抗心肌纤维化等多种细胞保护效应,还能促进高脂血症动物模型的胆固醇代谢和排泌等,对防治多种心血管疾病及血管介入治疗后再狭窄具有积极意义。现主要就牛磺酸对心血管系统保护作用及其机制的研究进展进行综述。 Taurine has a broad range of biological functions and has various cytoprotective effects such as repairing vascular endothelial function, anti-lipid peroxidation, reducing calcium overload, inhibiting vascular smooth muscle cell proliferation, inhibiting apoptosis, and anti-myocardial fibrosis, and can also promote Hyperlipidemia animal model of cholesterol metabolism and excretion, prevention and treatment of a variety of cardiovascular disease and vascular restenosis after intervention has a positive meaning. The research progress on the protective effect of taurine on cardiovascular system and its mechanism are reviewed.