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目的探讨儿童阻塞性睡眠呼吸暂停低通气综合征(OSAS)对血浆超敏C-反应蛋白(hs-CRP)含量的影响。方法选择多导联睡眠监护证实为OSAS的30例4～6岁患儿作为实验组,另外30例无OSAS的健康者为对照组,观察两组睡前和第2天清晨血浆hs-CRP的变化。结果两组患儿一般情况比较差异无统计学意义(P>0.05),两组患儿睡前和第2天清晨血浆hs-CRP含量比较差异无统计学意义(P>0.05)。结论 4～6岁儿童OSAS对血浆hs-CRP含量影响不大。
Objective To investigate the effect of obstructive sleep apnea-hypopnea syndrome (OSAS) on plasma hs-CRP level in children. Methods 30 cases of children aged 4 to 6 years who were confirmed as OSAS by polysomnography were selected as the experimental group. Another 30 healthy volunteers without OSAS served as the control group. The plasma hs-CRP levels in the two groups before and 2 days were observed Variety. Results There was no significant difference in general situation between the two groups (P> 0.05). There was no significant difference in plasma hs-CRP levels between the two groups before bedtime and on the second day before bedtime (P> 0.05). Conclusion OSAS in children aged 4 ~ 6 years has little effect on the plasma hs-CRP level.