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目的:探讨潘妥拉唑联合碳酸氢钠治疗胃结石的临床疗效和安全性。方法:经胃镜或钡餐造影确诊胃结石的21例患者,给予潘妥拉唑80 mg.d-1,分2次静脉点滴,及5%碳酸氢钠20 mL口服,tid。治疗后1周复查胃镜。如结石未消失,继续治疗1周。分析临床疗效与胃结石原因、大小、病程等的关系。结果:21例胃结石患者中柿石10例,黑枣4例,山楂4例,原因不清3例;病程在半月以内者14例,半月到1个月之间的2例,1月到3个月之间的2例,3月以上的3例;2~6 cm之间的结石15例,6 cm以上结石患者6例。14例(66.7%)患者药物治疗后结石消失,13例病程在半月以内,1例病程在1~3月;均为2~6 cm之间的结石;7例柿石,4例山楂石,1例黑枣石,2例原因不清。17例合并胃溃疡。药物治疗无效者经内镜或手术治疗。结论:药物治疗可作为胃结石首选治疗方法,特别是病程在半月以内者;对于病程长、较大的胃结石患者,药物治疗可缓解症状,减轻胃溃疡,便于进一步的内镜下治疗或手术治疗。
Objective: To investigate the clinical efficacy and safety of pantoprazole combined with sodium bicarbonate in the treatment of gastric stones. Methods: Twenty patients with gastric stones diagnosed by gastroscopy or barium meal angiography were given intravenous drip of pantoprazole 80 mg.d-1 twice daily and 20 mL of 5% sodium bicarbonate. 1 week after treatment review gastroscopy. If the stones have not disappeared, continue treatment for 1 week. Analysis of clinical efficacy and causes of gastric stones, size, duration of the relationship. Results: 21 cases of gastric stones in Persimmon stone in 10 cases, 4 cases of black dates, hawthorn in 4 cases, 3 cases of unclear; course of disease within half a month in 14 cases, half months to 1 month between 2 cases, January to 3 2 months between months, 3 cases above March; 15 cases of stones between 2 ~ 6 cm, 6 cases of stones above 6 cm. 14 cases (66.7%) patients disappeared after drug treatment, 13 cases of course of disease within a half months, 1 course of disease in January to March; all 2 to 6 cm between stones; 7 cases persimmon, 4 cases of hawthorn, 1 case of black date stone, 2 cases unclear. 17 cases with gastric ulcer. Medical treatment ineffective endoscopic or surgical treatment. Conclusion: Medication can be the preferred treatment for gastric stones, especially those with a duration of less than half a month. For patients with longer course of disease and larger stomach stones, the medication can relieve the symptoms, relieve the gastric ulcer and facilitate further endoscopic treatment or surgery treatment.