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脑卒中是世界的第二大致死原因,也仍然是致残的主要原因。基于基因技术的进步,本研究旨在评价一种RNA的表达对脑卒中预后预测的有效性。受试者纳入遵从于一个名为interstroke的研究设计方案。该研究方案为一个涉及22个国家的大型国际标准化病例对照研究。研究中,治疗组为129例脑卒中患者,对照组为170例没有脑卒中的患者。治疗组于患者出现症状后五天进行血液采样,所有患者提取总RNA后筛选与脑卒中相关的转录RNA。
Stroke is the second leading cause of death in the world and is still the leading cause of disability. Based on advances in genetic technology, this study aimed to evaluate the effectiveness of an RNA expression in prediction of stroke prognosis. Subjects were enrolled in a research design called interstroke. The research program is a large, internationally standardized case-control study involving 22 countries. In the study, there were 129 stroke patients in the treatment group and 170 patients without stroke in the control group. Blood samples were taken five days after symptom onset in the treatment group and all patients were screened for total RNA and stroke-related RNA was screened.